Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gram-negative bacterial endocarditis in narcotic addicts.

J E Rosenblatt, J G Dahlgren, R S Fishbach

    California Medicine
    |February 1, 1973
    PubMed
    Summary

    Bacterial endocarditis cases in drug users rose in 1971, with Gram-negative bacilli becoming a notable cause. Treatment was often unsuccessful, highlighting challenges in managing this severe infection.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Donor-transmitted toxoplasmosis in liver transplant recipients: a case report and literature review.

    Transplant infectious disease : an official journal of the Transplantation Society·2007
    Same author

    Real-time PCR in clinical microbiology: applications for routine laboratory testing.

    Clinical microbiology reviews·2006
    Same author

    Daptomycin: a novel agent for Gram-positive infections.

    Expert opinion on investigational drugs·2005
    Same author

    Health effects of diazinon on a family.

    Journal of toxicology. Clinical toxicology·2004
    Same author

    Comparison of the Roche LightCycler vanA/vanB detection assay and culture for detection of vancomycin-resistant enterococci from perianal swabs.

    Journal of clinical microbiology·2004
    Same author

    Real-time PCR method for detection of Encephalitozoon intestinalis from stool specimens.

    Journal of clinical microbiology·2002

    Area of Science:

    • Infectious Diseases
    • Cardiology
    • Microbiology

    Background:

    • Bacterial endocarditis is a serious heart valve infection.
    • Drug abuse is a known risk factor for endocarditis.
    • A rise in specific bacterial infections was observed in a clinical setting.

    Purpose of the Study:

    • To report an increase in bacterial endocarditis cases among intravenous drug users.
    • To identify the causative organisms, particularly Gram-negative bacilli.
    • To evaluate the efficacy of medical treatments for this patient population.

    Main Methods:

    • Retrospective analysis of endocarditis cases at UCLA and Wadsworth Veterans Administration hospitals.
    • Review of patient records from 1967-1971.
    • Identification of infecting organisms and assessment of treatment outcomes.

    Main Results:

    • A sharp increase in bacterial endocarditis cases was observed in 1971 compared to prior years.
    • Enteric Gram-negative bacilli were identified as the causative agent in 3 of 7 cases in 1971, a new finding.
    • Medical treatments, including newer antimicrobials, were largely unsuccessful.

    Conclusions:

    • Intravenous drug use is associated with a rise in bacterial endocarditis.
    • Enteric Gram-negative bacilli pose a significant challenge in treating endocarditis in this population.
    • Effective management may require aggressive interventions, including surgical treatment, for severe cases.

    Related Experiment Videos