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["Cold" nodules of the thyroid gland. (Clinical statistical study)]
Minerva Chirurgica
|June 30, 1979
Summary
This study analyzed 718 cold thyroid nodules, finding malignancy in 12.27%. For solitary cold nodules, unilateral lobectomy is recommended over total thyroidectomy to avoid hypothyroidism, except in anaplastic thyroid cancer.
Area of Science:
- Endocrinology
- Oncology
- Nuclear Medicine
Background:
- Cold thyroid nodules are often evaluated for malignancy.
- Previous studies have varied in their recommendations for surgical management.
Purpose of the Study:
- To analyze the incidence of malignancy in cold thyroid nodules.
- To evaluate the optimal surgical approach for solitary cold nodules.
- To correlate echotomographic findings with malignancy.
Main Methods:
- Retrospective analysis of 718 cold thyroid nodules.
- Surgical management and pathological outcomes were reviewed.
- Echotomographic features of nodules were assessed.
Main Results:
- Malignancy was found in 12.27% of cases (88/718).
- Papilliferous and follicular tumors were the most common malignancies.
- Echotomography demonstrated typical features suggestive of malignancy.
Conclusions:
- Unilateral lobectomy with suppressive therapy is preferred for solitary cold nodules due to low malignancy rates.
- Total thyroidectomy is reserved for anaplastic thyroid cancer.
- Echotomography is a valuable tool for preoperative diagnosis of thyroid cancer.