A molecular orbital study of 2,4,5-trihydroxyphenethylamine and related polyhydroxyphenethylamines

Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.

Journal of medicinal chemistry·2001

Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor.

Bioorganic & medicinal chemistry letters·2001

Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.

Journal of medicinal chemistry·2001

The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type.

Bioorganic & medicinal chemistry letters·2001

Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues.

Journal of medicinal chemistry·2001

Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.

Journal of medicinal chemistry·2000

Promotion of tumor cell senescence by the antibody-drug conjugate, sacituzumab govitecan.

Molecular pharmacology·2026

Molecular basis for state-dependent drug block of Kv11.1 (human ether-à-go-go-related gene) potassium channels.

Molecular pharmacology·2026

AKAP6β-a conductor in the orchestra of pathological cardiomyocyte gene transcription.

Molecular pharmacology·2026

ZD-4009, a novel B-cell lymphoma 9 inhibitor, is associated with ameliorated pulmonary fibrosis and reduced hypoxia-inducible factor 1α-mediated glycolysis and transforming growth factor-β/SMAD signaling.

Molecular pharmacology·2026

Piezo1 agonists are potent off-target inhibitors of the Kv1.3 channel via gating modification.

Molecular pharmacology·2026

Panoramic characterization of proposed ligands for GPR3: oleoylethanolamide as a pharmacological chaperone.

Molecular pharmacology·2026

Gas signaling molecule: a new research focus in the treatment of erectile dysfunction.

Medical gas research·2026

Ultrasound-assisted extraction of flavonoids from Blumea balsamifera using deep eutectic solvents: optimization, characterization, and antioxidant evaluation.

Ultrasonics sonochemistry·2026

Associations between Maillard α-dicarbonyl intermediates and aroma compounds in fragrant Camellia oleifera seed oil.

Food chemistry·2026

Sigmatropic rearrangements of ynamides in stereoselective synthesis of complex molecular architectures: a comprehensive review.

RSC advances·2026

A cyanidin-3-O-rutinoside dominant anthocyanin system from Osmanthus fragrans fruit peel: Composition, color behavior and thermal stability.

Food chemistry: X·2026

Averrhoa bilimbi L. Juice: An efficient natural acid catalyst for the green synthesis of dihydropyrimidinone-1,2,3-triazole.

MethodsX·2026

Related Experiment Videos

A molecular orbital study of 2,4,5-trihydroxyphenethylamine and related polyhydroxyphenethylamines

Related Concept Videos

Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.

Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor.

Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.

The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type.

Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues.

Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.

Promotion of tumor cell senescence by the antibody-drug conjugate, sacituzumab govitecan.

Molecular basis for state-dependent drug block of Kv11.1 (human ether-à-go-go-related gene) potassium channels.

AKAP6β-a conductor in the orchestra of pathological cardiomyocyte gene transcription.

ZD-4009, a novel B-cell lymphoma 9 inhibitor, is associated with ameliorated pulmonary fibrosis and reduced hypoxia-inducible factor 1α-mediated glycolysis and transforming growth factor-β/SMAD signaling.

Piezo1 agonists are potent off-target inhibitors of the Kv1.3 channel via gating modification.

Panoramic characterization of proposed ligands for GPR3: oleoylethanolamide as a pharmacological chaperone.

Gas signaling molecule: a new research focus in the treatment of erectile dysfunction.

Ultrasound-assisted extraction of flavonoids from Blumea balsamifera using deep eutectic solvents: optimization, characterization, and antioxidant evaluation.

Associations between Maillard α-dicarbonyl intermediates and aroma compounds in fragrant Camellia oleifera seed oil.

Sigmatropic rearrangements of ynamides in stereoselective synthesis of complex molecular architectures: a comprehensive review.

A cyanidin-3-O-rutinoside dominant anthocyanin system from Osmanthus fragrans fruit peel: Composition, color behavior and thermal stability.

Averrhoa bilimbi L. Juice: An efficient natural acid catalyst for the green synthesis of dihydropyrimidinone-1,2,3-triazole.

Related Experiment Videos

A molecular orbital study of 2,4,5-trihydroxyphenethylamine and related polyhydroxyphenethylamines

Related Concept Videos

Related Articles