[Electrographic changes in isolated cat cortex under the influence of sleep neuropeptide]

Experiments on adult cats with isolated cerebral cortex show that suboccipital olygopeptide administration (10 and 15 mg/kg) induces electrographic manifestation of the slow wave sleep (SWS) in the isolated cortex. Slow synchronous waves reflecting the onset of SWS appear in the isolated cortex 0.2-1.5 sec earlier than in the control hemisphere. The same administration prevents the onset of paradoxical sleep (PS) up to 2 hours from the beginning of the experiment. In all experiments, manifestation of the PS was recorded in both hemispheres simultaneously.