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Related Experiment Videos

Bacterial immunotherapy in bronchial asthma.

A Oehling, J Jerez, H Neffen

    Allergologia Et Immunopathologia
    |January 1, 1979
    PubMed
    Summary

    Bacterial vaccines show a 75% success rate in treating bacterial-induced asthma and bronchitis, with even higher efficacy in children. This immunotherapy approach is more effective than symptomatic treatment for these allergic respiratory conditions.

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    Area of Science:

    • Immunology
    • Pulmonology
    • Allergy

    Background:

    • Bacterial allergy is a significant factor in bronchospastic states like bacterial bronchial asthma and asthmatic bronchitis.
    • Traditional symptomatic treatment often overlooks the role of bacterial allergy.
    • Advances in immunotherapy highlight the importance of addressing bacterial allergies in respiratory diseases.

    Purpose of the Study:

    • To evaluate the effectiveness of bacterial vaccine immunotherapy in patients with bacterial-induced bronchial asthma and asthmatic bronchitis.
    • To assess the success rate of immunotherapy in different age groups, including children.
    • To investigate the prevalence of associated conditions like paranasal sinusitis.

    Main Methods:

    • A study involving 120 patients (59 women, 51 men, ages 7-73) diagnosed with bacterial bronchial asthma or asthmatic bronchitis.
    • Patients received bacterial vaccine immunotherapy.
    • Effectiveness was assessed via a questionnaire sent three years post-treatment initiation.

    Main Results:

    • Bacterial vaccine immunotherapy achieved a 75% success rate in treating bronchial disorders with bacterial allergy.
    • In children under 12, the success rate reached 90.47%.
    • Positive skin tests (83.32%) and associated paranasal sinusitis (83%) were common, indicating a sinobronchopulmonary syndrome.

    Conclusions:

    • Immunotherapy with bacterial vaccines is highly effective for primary bacterial bronchial asthma.
    • The treatment demonstrates superior value compared to prolonged symptomatic therapy.
    • Addressing bacterial allergy, often linked with sinusitis, is crucial for managing these respiratory conditions.

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