Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Auditory potentials of cochlear nerve and brain stem in multiple sclerosis.

E Shanon, S Gold, M Z Himmelfarb

    Archives of Otolaryngology (Chicago, Ill. : 1960)
    |September 1, 1979
    PubMed
    Summary

    This study found a unique auditory evoked potential pattern in multiple sclerosis (MS) patients, characterized by delayed brain stem conduction and altered wave responses, aiding in diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Apropos of digestive lymphosarcomatosis].

    Revue medicale de France·2014
    Same author

    Twenty-three-hour stay loop ileostomy closures: a pilot study.

    Techniques in coloproctology·2012
    Same author

    Enhanced recovery programmes; coming to a hospital near you!

    Anaesthesia·2011
    Same author

    Letters to the Editor.

    Postgraduate medical journal·2011
    Same author

    Toxemia of pregnancy and experimental hypertension; the production and the measurement of experimental renal hypertension.

    Revue canadienne de biologie·2010
    Same author

    Toxemia of pregnancy and experimental hypertension; the etiology of experimental hypertension.

    Revue canadienne de biologie·2010

    Area of Science:

    • Neuroscience
    • Clinical Neurology
    • Auditory Neuroscience

    Background:

    • Multiple sclerosis (MS) is a demyelinating disease affecting the central nervous system.
    • Auditory evoked potentials (AEPs) assess the integrity of the auditory pathway from the cochlear nerve to the brain stem.
    • Diagnosing MS can be challenging, necessitating reliable electrophysiological markers.

    Purpose of the Study:

    • To investigate the AEP characteristics in patients with suspected or confirmed multiple sclerosis.
    • To identify specific AEP patterns indicative of MS-related auditory pathway dysfunction.
    • To explore the clinical utility of AEPs in the diagnosis and management of MS.

    Main Methods:

    • Recording of auditory evoked potentials, including cochlear nerve and brain stem responses.

    Related Experiment Videos

  • Analysis of specific AEP waveform parameters, such as latencies and amplitudes.
  • Inclusion of ten patients with confirmed MS and four with suspected MS.

    • Main Results:

    • A consistent AEP pattern was observed in MS patients.
    • This pattern included a prolonged N1-P4 conduction time.
    • Absent or diminished N2 and/or N5 waves were frequently noted.

    Conclusions:

    • The identified AEP pattern serves as a potential electrophysiological biomarker for multiple sclerosis.
    • These findings suggest AEPs can help in the diagnosis of MS, particularly in cases with unclear clinical presentation.
    • Further research is warranted to fully elucidate the clinical implications and diagnostic accuracy of these AEP findings in MS.