Diffuse malignant ring melanoma of the iris and ciliary body

Area of Science:

• Ophthalmology
• Oncology

Background:

• Diffuse malignant ring melanoma is a rare intraocular tumor.
• Anterior uveal melanomas present unique diagnostic challenges.

Observation:

• Two cases of diffuse malignant ring melanoma of the anterior uvea are presented.
• Case 1 involved a correct clinical diagnosis leading to enucleation.
• Case 2 required enucleation two years post anti-glaucomatous surgery.

Findings:

• Histopathological confirmation of diffuse malignant ring melanoma.
• The clinical presentation can mimic other anterior uveal pathologies.
• Delayed diagnosis or treatment can impact management strategies.

Implications:

• Highlights the importance of early and accurate diagnosis of anterior uveal melanomas.
• Underscores the need for prompt surgical intervention (enucleation) in confirmed cases.
• Suggests considering melanoma in the differential diagnosis of unexplained anterior uveitis or glaucoma.