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Related Experiment Videos

Aminoglycoside serum assays restricted through a pharmacy program.

C W Greenlaw, S S Blough, R K Haugen

    American Journal of Hospital Pharmacy
    |August 1, 1979
    PubMed
    Summary
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    A pharmacy program successfully reduced inappropriate aminoglycoside serum assays by pharmacists intervening when tests lacked clear indications. This intervention ensured appropriate test use and improved patient care outcomes.

    Area of Science:

    • Clinical Pharmacy
    • Pharmacokinetics
    • Drug Monitoring

    Background:

    • Aminoglycoside serum assays are crucial for therapeutic drug monitoring.
    • Inappropriate ordering of these assays can lead to unnecessary costs and potential patient harm.
    • A structured program is needed to optimize the utilization of aminoglycoside assays.

    Purpose of the Study:

    • To describe and evaluate a pharmacy program aimed at reducing the inappropriate use of aminoglycoside serum assays.
    • To assess the impact of pharmacist intervention on the appropriateness of ordering and utilizing these assays.

    Main Methods:

    • Pharmacist review of all ordered aminoglycoside serum assays.
    • Intervention by pharmacists to discourage testing when clinical indications were not met.

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  • Pharmacist guidance on timing of sample collection and pharmacokinetic reporting when tests were appropriate.

    • Main Results:

    • During an 18-month evaluation, 67 tests were ordered for 53 patients.
    • Three tests were not performed due to pharmacist recommendations.
    • Of 59 evaluated tests, 95% were used appropriately, with 92% of appropriate decisions resulting from pharmacist recommendations.

    Conclusions:

    • The described pharmacy program effectively prevents problems associated with unrestricted aminoglycoside serum assay use.
    • Pharmacist-led interventions significantly improve the appropriate utilization of diagnostic laboratory tests.
    • This program serves as a model for optimizing drug monitoring assays in clinical practice.