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Evans blue dermatitis.

M A Guill, R B Odom

Archives of Dermatology

|September 1, 1979

Summary

This summary is machine-generated.

Evans blue dye, used in lymphangiography, caused contact dermatitis in five patients. Researchers propose a mechanism for this adverse skin reaction to the azo dye.

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Area of Science:

Dermatology
Radiology
Toxicology

Background:

Lymphangiography is a medical imaging procedure to visualize lymphatic vessels.
Evans blue is an azo dye utilized for outlining lymphatics during lymphangiography.
Contact dermatitis is an inflammatory skin reaction.

Observation:

Five patients developed contact dermatitis after undergoing lymphangiography.
The dermatitis was attributed to the use of Evans blue dye.
The timing of the reaction was associated with the dye application.

Findings:

Evans blue, an azo-type dye, is implicated as the causative agent for contact dermatitis.
A pathophysiologic mechanism for Evans blue-induced dermatitis is proposed.
The study highlights a potential adverse effect of Evans blue in clinical settings.

Implications:

Clinicians should be aware of the risk of contact dermatitis with Evans blue.
Further research may explore alternative dyes or preventative measures.
Understanding the mechanism can aid in managing or preventing similar reactions.