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Reversal of morphine tolerance after medial thalamic lesions in the rat
Science (New York, N.Y.)
|August 2, 1974
Abstract:
Tolerance, manifested by a diminished electroencephalographic response at cortical and subcortical recording sites, was found in rats subjected to repeated systemic injections of morphine sulfate. Reversal of tolerance to morphine resulted from destruction of the medial thalamus.