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Systemic thermotherapy (whole body hyperthermia).
International Journal of Clinical Pharmacology and Biopharmacy
|August 1, 1979
Summary
Whole Body Hyperthermia (WBHT) is an effective cancer treatment. In a study of 60 patients, WBHT showed significant objective and subjective responses with manageable side effects, confirming its safety and feasibility.
Area of Science:
- Oncology
- Therapeutic Technologies
Background:
- Whole Body Hyperthermia (WBHT) is an emerging cancer treatment modality.
- Limited data exists on its safety and efficacy in clinical settings.
Purpose of the Study:
- To review the literature and present initial findings on WBHT for cancer treatment.
- To evaluate the safety, feasibility, and efficacy of WBHT in a cohort of 60 patients.
Main Methods:
- Patients underwent WBHT for a total of eight hours, with temperatures reaching 180 degrees F for two hours.
- WBHT was administered using high-flow water-filled blankets under closely monitored conditions.
Main Results:
- Objective response rate was 50%, and subjective response rate was 65%.
- Common toxicities included fatigue, nausea, diarrhea, and first-degree burns.
- No visceral damage or procedure-related mortalities were observed.
Conclusions:
- WBHT is a feasible, safe, and active anti-cancer therapy when administered under strict monitoring.
- WBHT can be safely used as an adjunct to conventional cancer therapies like radiation and chemotherapy.