Cross-agglutination reaction in Candida albicans and enteric bacilli

Cross-reactivity between Candida albicans and representative Enterobacteriaceae was investigated by agglutination methods. It was observed that anti-Candida serum reacted to certain groups of salmonellae and shigellae. The only antiserum against the enteric bacilli that reacted with Candida was Salmonella C(1). When anti-Candida serum was adsorbed with C. albicans or S. montevideo, all the activity was removed. However, when the anti-Salmonella serum was adsorbed with the antigens, Salmonella adsorbed the whole antibody activity, whereas Candida removed only its corresponding antibody.