[Differential pharmacotherapy of neurotic conditions (comparative effectiveness of benzodiazepine derivatives)]

The effectiveness in treating borderline states to a certain degree depends upon the pole (sthenic or asthenic) of the corresponding disturbance. Tranquilizers are the preparations of choice in the treatment of disorders of an asthenic pole (psychopathy of the asthenic range, neurotic states). In borderline conditions of a sthenic pole the effectiveness of tranquilizers is equal or sometimes is even less than in therapy with small doses of neuroleptics. In treating neurotic conditions tranquilizers of the benzodiazepine group can be ranged in the following succession: nitrazepam, chlordiazepoxide, medazepam, oxazepam, diazepam, lorazepam. This preparation is a continuun of an increasing psychotropic activity.