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Analysis of ethylene oxide--worker exposure.

S J Romano, J A Renner

American Industrial Hygiene Association Journal

|August 1, 1979

Summary

A new personal air sampling method accurately measures worker exposure to ethylene oxide (EtO) by converting it to ethylene glycol. This technique offers advantages over existing methods for assessing workplace EtO exposure.

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Area of Science:

Occupational Health and Safety
Analytical Chemistry
Environmental Monitoring

Background:

Ethylene oxide (EtO) is a widely used industrial chemical with significant occupational health risks.
Accurate personal air sampling is crucial for assessing worker exposure to EtO.
Existing methods may have limitations in terms of accuracy, convenience, or scope.

Purpose of the Study:

To develop and validate a novel personal air sampling method for quantifying individual worker exposure to ethylene oxide.
To establish a reliable and efficient technique for monitoring workplace EtO levels.

Main Methods:

Developed a personal air sampling method involving trapping ethylene oxide (EtO) in dilute sulfuric acid.
Converted trapped EtO to ethylene glycol for subsequent analysis.
Utilized gas chromatography with a specific glass column (5% Igepal CO-990 on Teflon T-6) for precise ethylene glycol determination.

Main Results:

The developed method demonstrated high recovery rates of 94.2% for ethylene oxide within the 1 to 8 ppm concentration range.
The gas chromatography column provided linear calibration curves and symmetrical peaks, indicating method robustness.
The sampling technique proved independent of flow rate and sample size, enhancing its versatility.

Conclusions:

The new personal air sampling method is effective for assessing worker exposure to ethylene oxide.
This method offers advantages compared to the current NIOSH method, potentially improving occupational exposure assessments.
The technique's independence from flow and sample size makes it a practical tool for diverse workplace environments.

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