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Intraoperative transmural myocardial biopsy: a simple technique
Canadian Journal of Surgery. Journal Canadien De Chirurgie
|September 1, 1979
Summary
A simple and safe biopsy technique using a Tru-cut needle successfully obtained full-thickness ventricular myocardium from pigs, cadavers, and humans for research. This method provides adequate tissue for detailed diagnostic analysis, including microscopy and biochemical studies.
Area of Science:
- Cardiovascular Research
- Biopsy Techniques
- Histopathology
Background:
- Transmural ventricular myocardium sampling is crucial for cardiac research and diagnostics.
- Existing biopsy methods may have limitations in tissue acquisition or safety.
Purpose of the Study:
- To evaluate the simplicity and safety of a Tru-cut disposable biopsy needle for obtaining transmural ventricular myocardium.
- To assess the adequacy of the obtained myocardial tissue for various diagnostic and research applications.
Main Methods:
- A Tru-cut disposable biopsy needle was employed.
- The procedure was performed on 10 pigs, 3 cadavers, and 63 human subjects.
- Tissue analysis included light and electron microscopy, enzyme studies, and glycogen measurement.
Main Results:
- The Tru-cut biopsy technique was demonstrated to be simple and safe across all subjects.
- Adequate amounts of full-thickness ventricular myocardium were consistently obtained.
- The harvested tissue was suitable for comprehensive diagnostic evaluations.
Conclusions:
- The Tru-cut disposable biopsy needle is an effective tool for acquiring transmural ventricular myocardium.
- This technique offers a safe and reliable method for obtaining cardiac tissue for research and diagnostic purposes.