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Sarcocystis: development in cultured avian and mammalian cells
Science (New York, N.Y.)
|May 29, 1970
Abstract:
Sarcocystis, a protozoan that parasitizes muscle tissue of reptiles, birds, and mammals, including man, developed in avian and mammalian cell cultlures. Mctile banana-shaped organisms, released from cysts in grackle muscle, entered cells and transformed into enlarged ellipsoid or oblong stages, which developed into either multinucleate or cyst-like stages, or both.
Insights
Sarcocystis, a protozoan parasite, successfully developed in avian and mammalian cell cultures. The study observed its transformation from motile forms to multinucleate or cyst-like stages within host cells.
Area of Science:
- Parasitology
- Cell Biology
- Veterinary Science
Background:
- Sarcocystis is a protozoan parasite affecting various animal species and humans.
- Understanding Sarcocystis development is crucial for disease control and prevention.
Purpose of the Study:
- To investigate the in vitro development of Sarcocystis in cell cultures.
- To characterize the morphological transformations of Sarcocystis within host cells.
Main Methods:
- Avian and mammalian cell cultures were utilized.
- Motile Sarcocystis organisms were isolated from grackle muscle tissue.
- Developmental stages were observed following cell entry.
Main Results:
- Sarcocystis developed successfully in both avian and mammalian cell cultures.
- Motile, banana-shaped organisms transformed into enlarged ellipsoid or oblong stages.
- These stages further developed into multinucleate or cyst-like forms, or both.
Conclusions:
- Cell culture provides a viable model for studying Sarcocystis development.
- Sarcocystis exhibits distinct morphological changes during its intracellular lifecycle.