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Ultrastructural observation of rickettsia-like bodies in erythema cronicum migrans
Journal of Cutaneous Pathology
|August 1, 1979
Abstract:
Electron microscopic examination of skin biopsies taken from the lesions in two cases of erythema chronicum migrans revealed Rickettsia-like bodies free in the cytoplasm or within phagolysosomes in macrophages. There was also phagocytosis of cellular debris and collagen, and elastic fibers within macrophages.
Insights
Electron microscopy revealed Rickettsia-like organisms in erythema chronicum migrans (ECM) skin lesions. These findings suggest a potential role for these bacteria in ECM pathogenesis.
Area of Science:
- Microbiology
- Dermatology
- Pathology
Background:
- Erythema chronicum migrans (ECM) is a characteristic skin manifestation of Lyme disease.
- The causative agent of Lyme disease, Borrelia burgdorferi, is a spirochete.
- The presence of other microorganisms in ECM lesions has been investigated.