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[Contribution to the study of Trive 1000]
Annales De L'Anesthesiologie Francaise
|December 1, 1975
Summary
Trive 1000, a glucid-lipid-protein nutriment, demonstrated good local tolerance in postoperative patients. Higher doses correlated with more positive nitrogen balances, indicating satisfactory protein assimilation and carbohydrate utilization.
Area of Science:
- Nutritional biochemistry
- Clinical nutrition
- Postoperative care
Context:
- Postoperative nutrition is crucial for recovery.
- Parenteral nutrition aims to provide essential nutrients during critical periods.
- Trive 1000 is a compound nutriment for postoperative patients.
Purpose:
- To evaluate the efficacy and tolerance of Trive 1000 in postoperative patients.
- To assess the metabolic impact of Trive 1000 on glucides, proteins, and lipids.
- To determine the optimal dosage for nitrogen balance and nutrient assimilation.
Summary:
- Trive 1000 was administered to 53 postoperative patients over three days at two different dosages.
- Metabolic assessments included glucides (Sorbitol), proteins, lipids, and amino acids.
- Good local tolerance was observed; general adverse events were linked to improper storage.
- Carbohydrate assimilation was effective with normal glycemia and no glycosuria or ketonuria.
- Protein assimilation was satisfactory, with positive nitrogen balances correlating with higher Trive 1000 doses.
- Lipid profiles showed minimal changes, with transient chylomicrons and altered pre-beta lipoproteins.
- Essential amino acid levels remained stable, while non-essential amino acid urinary clearance varied significantly post-administration.
Impact:
- Trive 1000 shows promise as a parenteral nutritional support in the postoperative period.
- Dosage optimization may enhance nitrogen retention and patient recovery.
- Further research is needed to understand the variability in amino acid clearance.