[Kinetic study of a heterogeneous tumor cell population using a mathematical model]

A mathematical model of a heterogenous tumor as a system of interrelating cell populations is described, including a pool of quiescent cells, cell-to-cell variability in maturation rates, and cell migration from growth area to necrotic one. Computer simulation results are given, model labeled mitoses and labeled index curves for the Lewis carcinoma are compared with experimental data.