[Dynamics of the total proteolytic activity and kinin system components of the blood in acute cholecystitis]

Under study was the dynamics of changes of the activity of components of the kinin system and proteolytic activity of blood in 32 patients with acute cholecystitis. The results have shown that cholecystic patients and patients with the diseases of biliary ducts, especially in the exacerbation stage, have pronounced shifts in the kinin system components and in the proteolytic activity of blood as a whole. In clinical conditions the proteolytic activity data can be used for determining the severity and development of acute cholecystitis. The use of protease inhibitors in the inflammation of the gallbladder and biliary ducts results in a decreased blood proteolytic activity and thereby contributes to more rapid recovery of patients with such disorders.

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