Effects of anthramycin and actinomycin on RNA synthesis patterns in L1210 cells

Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).

Oncogene·2007

p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Oncogene·2006

Quantitative structure-antitumor activity relationships of camptothecin analogues: cluster analysis and genetic algorithm-based studies.

Journal of medicinal chemistry·2001

How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair?

Cell biochemistry and biophysics·2001

Molecular and biological determinants of the cytotoxic actions of camptothecins. Perspective for the development of new topoisomerase I inhibitors.

Annals of the New York Academy of Sciences·2001

Effects of c-erbB2 overexpression on the drug sensitivities of normal human mammary epithelial cells.

Journal of the National Cancer Institute·2000

Resveratrol Inhibits Macrophage Glucose Metabolism Reprogramming and Inflammatory Activation to Delay COPD Progression Through the TLR4/HK2 Pathway.

Journal of cellular physiology·2026

Induced Pluripotent Stem Cell-Derived Small-Diameter Vascular Grafts: Scaffold Design, Immune Engineering, and Clinical Translation.

Journal of cellular physiology·2026

Gut-Intervertebral Disc Axis: Gut Microbiome-Driven Immune-Metabolic Imbalance and Intervertebral Disc Degeneration.

Journal of cellular physiology·2026

Adenylyl Cyclase (ADCY) Protein Family: Molecular Mechanisms and Therapeutic Potential in Glucose and Lipid Metabolism and Feeding Regulation.

Journal of cellular physiology·2026

Simulated Microgravity Induced Mesenchymal Stem Cell Senescence via the Activation of Cytosolic mtDNA-cGAS-STING Axis.

Journal of cellular physiology·2026

Hippo Pathway Regulation and Microenvironmental Cues Governing Human MSC Transition to Cancer-Associated Fibroblasts.

Journal of cellular physiology·2026

Design of a variable energy linac for alpha particle acceleration and medical radioisotope production.

The Review of scientific instruments·2026

Dosimetric comparison of HDR Co-60 and Ir-192 brachytherapy sources by model-based dose calculation algorithms and its clinical implication in different brachytherapy sites and techniques.

Brachytherapy·2026

First Measurement of the Decay-Time-Integrated CP Asymmetry in B_{s}^{0}→D_{s}^{-}π^{+} Decays.

Physical review letters·2026

Survival of dipeptides under ionizing radiation in astrophysical environments.

Physical chemistry chemical physics : PCCP·2026

Impact of beam hardening on proton stopping-power ratio estimation using photon-counting, dual-energy, and single-energy computed tomography.

Physics and imaging in radiation oncology·2026

Novel analysis of proton- γ coincidences for the β -delayed proton emission technique: the case of 46 Mn.

The European physical journal. A, Hadrons and nuclei·2026

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Effects of anthramycin and actinomycin on RNA synthesis patterns in L1210 cells

Related Concept Videos

Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).

p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Quantitative structure-antitumor activity relationships of camptothecin analogues: cluster analysis and genetic algorithm-based studies.

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Gut-Intervertebral Disc Axis: Gut Microbiome-Driven Immune-Metabolic Imbalance and Intervertebral Disc Degeneration.

Adenylyl Cyclase (ADCY) Protein Family: Molecular Mechanisms and Therapeutic Potential in Glucose and Lipid Metabolism and Feeding Regulation.

Simulated Microgravity Induced Mesenchymal Stem Cell Senescence via the Activation of Cytosolic mtDNA-cGAS-STING Axis.

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Dosimetric comparison of HDR Co-60 and Ir-192 brachytherapy sources by model-based dose calculation algorithms and its clinical implication in different brachytherapy sites and techniques.

First Measurement of the Decay-Time-Integrated CP Asymmetry in B_{s}^{0}→D_{s}^{-}π^{+} Decays.

Survival of dipeptides under ionizing radiation in astrophysical environments.

Impact of beam hardening on proton stopping-power ratio estimation using photon-counting, dual-energy, and single-energy computed tomography.

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Effects of anthramycin and actinomycin on RNA synthesis patterns in L1210 cells

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