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Related Experiment Videos

Human tear pH. Diurnal variations.

L G Carney, R M Hill

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |May 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Tear pH exhibits diurnal patterns and individual variations in acidity. Prolonged eye closure significantly increases tear acidity compared to waking hours.

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    Area of Science:

    • Ophthalmology
    • Physiology
    • Biomedical Engineering

    Background:

    • Tear film pH is crucial for ocular surface health and comfort.
    • Understanding diurnal variations in tear pH is important for diagnosing and managing ocular surface diseases.

    Purpose of the Study:

    • To investigate diurnal patterns of tear pH in healthy subjects.
    • To determine the effect of prolonged eye closure on tear pH.

    Main Methods:

    • A closed chamber microelectrode system was used to monitor tear pH.
    • Tear pH was recorded for sixteen subjects over five waking days.
    • pH levels after prolonged eye closure were compared to waking hours.

    Main Results:

    • Significant inter-subject variations in absolute mean tear pH were observed.

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  • Diurnal patterns of tear pH change were identified in most subjects.
  • Tear pH was significantly more acidic after prolonged eye closure than during waking hours.

    • Conclusions:

    • Individual diurnal patterns of tear pH exist.
    • Prolonged eye closure leads to increased tear acidity, potentially impacting ocular surface homeostasis.