Quantitative serum levels of pregnancy associated alpha2-globulin in patients with benign and malignant tumours

Pregnancy associated alpha2-globulin estimations were made in the serum of 100 tumour-cases. This characteristically pregnancy protein could be found in 63 p.c. of the tumour cases. The number of positive sera was higher, than in normal controls. The serum level of pregnancy associated alpha 2-globulin was between 1 and 10 mg p.c. in 34 cases, between 11 and 20 mg p.c. in 19 cases and value above 20 mg p.c. could only be found in 10 patients. This alpha2-globulin positivity could be seen more frequently in female than in male patients. Role and significance of alpha2-globulin is discussed.