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Related Experiment Videos

Evaluation of hand cleansers.

R L Dobson

    Contact Dermatitis
    |September 1, 1979
    PubMed
    Summary

    Baracaide significantly reduced transepidermal water loss (TWL) compared to other industrial hand cleansers. This suggests Baracaide may better protect the skin barrier by avoiding volatile solvents.

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    Area of Science:

    • Dermatology
    • Occupational Health
    • Cosmetic Science

    Background:

    • Industrial hand cleansers are essential for removing grease and grime.
    • Some cleansers can disrupt the skin's natural barrier, leading to increased transepidermal water loss (TWL).
    • Evaluating the impact of different cleansers on skin barrier function is crucial for occupational health.

    Purpose of the Study:

    • To compare the effects of three industrial hand cleansers (Baracaide, Swarfega, Go-Jo) on transepidermal water loss (TWL).
    • To assess the efficacy of Baracaide in maintaining skin barrier integrity in an occupational setting.

    Main Methods:

    • Healthy volunteers were assigned to use specific industrial hand cleansers.
    • Transepidermal water loss (TWL) was measured after a 2-week period.
    • A second study specifically evaluated Baracaide's effect on TWL in printers.

    Main Results:

    • Subjects using Baracaide showed significantly lower TWL compared to Swarfega (47% less) and Go-Jo (35% less) after 2 weeks.
    • In printers, Baracaide use resulted in a 20% decrease in TWL over 2 weeks.
    • Baracaide contains no volatile solvents, unlike some other cleansers.

    Conclusions:

    • Baracaide demonstrates superior performance in reducing transepidermal water loss (TWL) compared to Swarfega and Go-Jo.
    • The absence of volatile solvents in Baracaide may contribute to its reduced impact on the skin's barrier layer.
    • Baracaide is a potentially less injurious option for industrial hand hygiene, preserving skin barrier function.

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