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Improved assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase

S Goldfarb, H C Pitot

Journal of Lipid Research

|July 1, 1971

Abstract:

Two improvements are described for the assay of HMG CoA reductase. These are a simple synthesis of the substrate precursor HMG-3-(14)C anhydride and a double-label ((14)C and (3)H) method for determining the amount of mevalonate-3-(14)C that is formed from the substrate.

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