Twins with Pierre Robin syndrome

An increasing number of case reports have drawn attention to the familial occurrence of the Pierre Robin syndrome. Postmortem studies on male twins concordant for the syndrome are reported. In addition to the triad of micrognathia, cleft palate and glossoptosis, both twins presented low-set malformed ears. Roentgencephalometric measurements suggested that the extreme micrognathia present in the twins precluded survival. An older sib with similar deformities also died in infancy.