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Updated: Aug 12, 2026

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Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Hydrogel lens power and oxygen transmissibility
Summary
Oxygen transmissibility in hydrogel contact lenses varies with lens power. High plus lenses show higher oxygen transmissibility than expected, while high minus lenses show lower, impacting clinical estimations.
Area of Science:
- Ophthalmic optics
- Biomaterials science
Background:
- Oxygen transmissibility is crucial for contact lens safety and comfort.
- Center thickness is a primary factor influencing oxygen transmissibility.
- The relationship between center thickness and oxygen transmissibility may be influenced by lens power.
Purpose of the Study:
- To investigate the relationship between oxygen transmissibility and center thickness in hydrogel contact lenses across different dioptric powers.
- To determine if lens power affects the correlation between center thickness and oxygen transmissibility.
- To provide clinically relevant insights for estimating oxygen transmissibility in high-power lenses.
Main Methods:
- Oxygen transmissibility measurements were conducted on hydrogel lenses.
- Lenses with varying dioptric powers (low, high plus, high minus) were tested.
- Data analysis focused on the correlation between center thickness, lens power, and measured oxygen transmissibility.
Main Results:
- A non-linear relationship exists between center thickness and oxygen transmissibility.
- High plus power lenses exhibited higher oxygen transmissibility than predicted by center thickness alone.
- High minus power lenses demonstrated lower oxygen transmissibility than predicted by center thickness alone.
Conclusions:
- Lens power significantly modifies the impact of center thickness on oxygen transmissibility.
- Accurate estimation of oxygen transmissibility for high-power contact lenses requires consideration of both center thickness and dioptric power.
- These findings have implications for contact lens material development and clinical prescription practices.

