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Updated: Sep 28, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
[Carcinoma of the hypopharynx as late sequel to x-ray exposure (author's transl)]
Abstract:
Two cases of x-ray induced carcinomas of the hypopharynx after radiation treatment of a struma some decades ago are described. Therefore widespread application of x-ray radiation in the treatment of benign tumours should be avoided. On account of a serious local damage of the skin in both patients the administration of an immoderate dosage must be supposed. This observation seems to be especially remarkable because these patients have been irradiated in the forties which is much earlier than other x-ray induced carcinomas reported in the literature.
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