[Effect of hemodialysis on the creatine kinase activity in inflammatory muscular diseases]

In 10 patients with polymyositis at different stages of the intensity of clinical changes the effect of serum dialysis on CPK activity was studied. The controlgroup comprised 5 patients with Duchenne type myopathy and 11 healthy subjects. In 80% of patients with polymyositis a fall in CPK activity was observed after dialysis, similarly as in all patients with Duchenne type dystrophy and in healthy subjects. In the ramaining patients with polymyositis a significant rise in CPK activity occurred after dialysis. These patients were in the acute stage of the disease and had not yet been treated.