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Related Experiment Videos

Herpes zoster in infancy.

T J David, M L Williams

    Scandinavian Journal of Infectious Diseases
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Infant herpes zoster (shingles) can occur when mothers contract chickenpox during pregnancy. This report details three such cases, highlighting a potential link between maternal varicella infection and neonatal shingles.

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    Area of Science:

    • Virology
    • Pediatrics
    • Dermatology

    Background:

    • Herpes zoster, commonly known as shingles, is caused by the reactivation of the varicella-zoster virus (VZV).
    • Congenital or neonatal varicella infections can occur following maternal primary VZV infection during pregnancy.

    Observation:

    • This report presents three distinct cases of infants diagnosed with herpes zoster.
    • In all three cases, the mothers had a history of chickenpox (varicella) infection during their pregnancies.

    Findings:

    • The occurrence of herpes zoster in infancy suggests a potential vertical transmission or in utero reactivation of VZV.
    • Maternal chickenpox during pregnancy appears to be a significant risk factor for neonatal herpes zoster.

    Implications:

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    • These cases underscore the importance of maternal varicella vaccination to prevent congenital and neonatal infections.
    • Further research is warranted to elucidate the mechanisms of VZV transmission and reactivation in the context of pregnancy and infancy.