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Clinical aspects of carotid sinus hyperaesthesia
Acta Medica Academiae Scientiarum Hungaricae
|January 1, 1979
Summary
Carotid sinus hyperaesthesia (CSH) is common and often involves impulse disorders. Digoxin can sensitize the carotid sinus reflex, suggesting decreased sympathetic efferentation plays a key role in CSH.
Area of Science:
- Cardiology
- Neurology
Background:
- Carotid sinus hyperaesthesia (CSH) is a condition characterized by an exaggerated response to stimuli affecting the carotid sinus.
- Patients with CSH frequently exhibit disorders of cardiac impulse formation and conduction.
Purpose of the Study:
- To investigate the prevalence and characteristics of impulse disorders in patients with CSH.
- To explore the effects of carotid sinus manipulation and pharmacological agents on arrhythmia in CSH patients.
- To elucidate the role of sympathetic efferentation in CSH.
Main Methods:
- Observation of 605 clinical cases with CSH over a 6-year period.
- Carotid compression tests at rest and during i.v. digoxin administration.
- Unilateral carotid sinus infiltration with lidocaine in 8 cases.
Main Results:
- Prevalence of impulse formation and conduction disorders in CSH patients.
- No correlation found between carotid compression duration and rhythm disorders.
- Vascular state did not influence arrhythmia type, duration, or severity.
- Lidocaine infiltration did not induce sympathicotonia or provoke arrhythmia.
- Digoxin administration confirmed carotid sinus reflex sensitization.
Conclusions:
- CSH is associated with prevalent impulse and conduction disorders.
- The findings suggest a significant role for decreased sympathetic efferentation in CSH.
- Carotid sinus reflex sensitization can be achieved with digoxin.