Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nonlinear least-squares regression programs for microcomputers.

C C Peck, B B Barrett

    Journal of Pharmacokinetics and Biopharmaceutics
    |October 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Lay descriptions of painful temporomandibular disorders-an international consensus proposal for Global Burden of Disease estimates.

    BMC medicine·2026
    Same author

    Response to Letter to Editor: "Disability Weights for Global Burden Estimation of Orofacial Pain".

    Journal of dental research·2026
    Same author

    Disability Weights for Global Burden Estimation of Orofacial Pain.

    Journal of dental research·2025
    Same author

    Circulating Interleukin-6 Is Associated with Skeletal Muscle Strength, Quality, and Functional Adaptation with Exercise Training in Mobility-Limited Older Adults.

    The Journal of frailty & aging·2020
    Same author

    Altered regional brain T2 relaxation times in individuals with chronic orofacial neuropathic pain.

    NeuroImage. Clinical·2018
    Same author

    Disruption of default mode network dynamics in acute and chronic pain states.

    NeuroImage. Clinical·2017
    Same journal

    Integrated equation to evaluate accumulation profiles of drugs eliminated by Michaelis-Menten kinetics.

    Journal of pharmacokinetics and biopharmaceutics·2010
    Same journal

    Applications of a recirculatory stochastic pharmacokinetic model: limitations of compartmental models.

    Journal of pharmacokinetics and biopharmaceutics·2010
    Same journal

    Effect of plasma protein and tissue binding on the time course of drug concentration in plasma.

    Journal of pharmacokinetics and biopharmaceutics·2010
    Same journal

    Pharmacokinetics of methotrexate in solid tumors.

    Journal of pharmacokinetics and biopharmaceutics·2010
    Same journal

    Single- and multiple-dose kinetics of oral lorazepam in humans: the predictability of accumulation.

    Journal of pharmacokinetics and biopharmaceutics·2010
    Same journal

    Comparison of the in vitro and in vivo release of digoxin from four different soft gelatin capsule formulations.

    Journal of pharmacokinetics and biopharmaceutics·2010
    See all related articles

    Nonlinear least-squares regression is feasible on microcomputers using BASIC. This study details existing BASIC programs and contrasts microcomputer with mainframe regression capabilities.

    Area of Science:

    • Computational chemistry
    • Scientific computing
    • Data analysis

    Background:

    • Nonlinear least-squares regression is a powerful statistical method.
    • Traditionally, complex regression analyses required mainframe computers.
    • Advancements in microcomputer technology enable sophisticated computations.

    Purpose of the Study:

    • To assess the feasibility of performing nonlinear least-squares regression on microcomputers.
    • To describe existing BASIC programs for nonlinear regression on microcomputers.
    • To compare microcomputer-based regression with traditional mainframe approaches.

    Main Methods:

    • Review of existing nonlinear regression programs written in BASIC.
    • Implementation and testing of two such programs on microcomputers.

    Related Experiment Videos

  • Comparative analysis of performance and resource requirements.

    • Main Results:

    • At least five nonlinear regression programs in BASIC were identified.
    • Two programs were successfully implemented and characterized on microcomputers.
    • Identified advantages and disadvantages of microcomputer-based nonlinear regression.

    Conclusions:

    • Microcomputers with BASIC and sufficient memory (8K+ bytes) can perform nonlinear least-squares regression.
    • Specific BASIC programs offer viable alternatives to mainframe regression for certain applications.
    • Microcomputer regression presents a cost-effective and accessible option for researchers.