Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Digitalis in pneumonectomy and its implication.

O A Adebo, A K Singh

    Journal of the National Medical Association
    |July 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Haemodynamic effects of pan masala in healthy volunteers.

    The Journal of the Association of Physicians of India·2001
    Same author

    A randomized comparison of classical mode of administration of amphotericin B with its newer modes of administration in kala-azar.

    The Journal of the Association of Physicians of India·2001
    Same author

    Relaxin decreases renal interstitial fibrosis and slows progression of renal disease.

    Kidney international·2001
    Same author

    A polystyrene based membrane electrode for cadmium(II) ions.

    Fresenius' journal of analytical chemistry·2001
    Same author

    The circadian pattern of ischaemic heart disease events in Indian population.

    The Journal of the Association of Physicians of India·2001
    Same author

    Amberlite XAD-7 impregnated with Xylenol Orange: a chelating collector for preconcentration of Cd(II), Co(II), Cu(II), Ni(II), Zn(II) and Fe(III) ions prior to their determination by flame AAS.

    Fresenius' journal of analytical chemistry·2001

    Preoperative digitalis significantly reduces arrhythmia and mortality in patients over 50 undergoing pneumonectomy. This cardiac medication is indicated to improve outcomes after major lung surgery.

    Area of Science:

    • Cardiology
    • Thoracic Surgery
    • Pharmacology

    Background:

    • Pneumonectomy, a major lung surgery, is associated with postoperative complications.
    • Arrhythmia and hemodynamic deterioration are significant risks following pneumonectomy, particularly in older patients.
    • The role of preoperative digitalis in mitigating these risks remains an area of investigation.

    Purpose of the Study:

    • To evaluate the effect of preoperative digitalis administration on the incidence of arrhythmia and mortality in patients over 50 years of age undergoing pneumonectomy.
    • To compare outcomes between patients receiving digitalis preoperatively versus those treated only after arrhythmia onset.

    Main Methods:

    • Retrospective analysis of 87 patients who underwent pneumonectomy between 1968 and 1977.

    Related Experiment Videos

  • Analysis focused on 68 patients over age 50, divided into two groups: Group 1 (digitalis initiated post-arrhythmia) and Group 2 (preoperative digitalis).
  • Outcomes assessed included postoperative arrhythmia incidence, hemodynamic deterioration, and hospital mortality.

    • Main Results:

    • Overall, 29% of patients developed postoperative arrhythmia, with a 10% hospital mortality rate.
    • In Group 1 (no preoperative digitalis), 45% developed arrhythmia, and 22% (4/18) died.
    • In Group 2 (preoperative digitalis), only 21% developed arrhythmia, with no associated deaths.

    Conclusions:

    • Preoperative digitalis administration is associated with a significantly lower incidence of arrhythmia following pneumonectomy in patients over 50.
    • The findings strongly suggest that preoperative digitalis is indicated in older patients undergoing pneumonectomy to reduce the risk of arrhythmia and mortality.
    • Prophylactic use of digitalis may improve perioperative outcomes in this high-risk surgical population.