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Related Experiment Videos

CT fogging effect with ischemic cerebral infarcts.

H Becker, H Desch, H Hacker

    Neuroradiology
    |October 31, 1979
    PubMed
    Summary

    The fogging effect describes how cerebral infarcts change appearance on CT scans over time. Understanding this phenomenon is crucial for accurate diagnosis and appropriate use of contrast-enhanced CT imaging.

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    Area of Science:

    • Neurology
    • Radiology
    • Medical Imaging

    Background:

    • Ischemic cerebral infarcts present diagnostic challenges on computed tomography (CT).
    • The evolving appearance of infarcts can lead to misinterpretation.
    • The 'fogging effect' is a poorly understood CT imaging phenomenon in stroke patients.

    Purpose of the Study:

    • To systematically investigate and describe the fogging effect in ischemic cerebral infarcts.
    • To determine the clinical significance of the fogging effect for CT interpretation.
    • To evaluate the necessity of contrast-enhanced CT for stroke diagnosis.

    Main Methods:

    • Systematic CT imaging studies were conducted on ten patients.
    • Patients had persistent ischemic cerebral infarcts.
    • Serial CT scans were analyzed to observe changes in infarct appearance over time.

    Main Results:

    • A consistent phenomenon, termed the fogging effect, was observed in ischemic cerebral infarcts.
    • Initially hypodense infarcts became isodense or near-isodense during the second to third weeks post-onset.
    • The fogging infarcted area demonstrated homogeneous, intensive contrast enhancement.
    • Infarcts reverted to a hypodense appearance at later stages.

    Conclusions:

    • The fogging effect is a critical consideration for interpreting CT images of cerebral infarction.
    • Knowledge of this effect is vital for appropriate contrast medium administration in CT.
    • Non-contrast CT scans may lead to misdiagnosis of cerebral infarction between the second and third weeks.

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