Effect of dimethylaminomethylendiphosphonate on the immobilisation osteoporosis in rats

The influence of the immobilization on the bone by the resection of the N. ischiadicus has been examined in rats, 130--150 g and 400 g of weight. The simultaneous administration of dimethylaminomethylendiphosphonate uses to lower the differences in respect to osteodissimilation between the immobilized and not immobilized extremity, caused by immobilization.