Potential fungicidal and bactericidal agents. Synthesis of certain 4-(2-amino-1,3,4-thiadiazol-5-yl)quinolines

The synthesis of some new 4-[2-alkyl (aryl or aralkyl) amino-1,3,4-thiadiazol-5-yl]-2-substituted quinolines is described. IR, UV, NMR and MS data of representative examples are discussed. Most of the compounds prepared showed a reasonable antifungal and antimicrobial activity.