Potential naphthoquinone antimalarials. 2-acylhydrazino-1,4-naphthoquinones

Does intranasal dexmedetomidine provide adequate plasma concentrations for sedation in children: a pharmacokinetic study.

British journal of anaesthesia·2018

Necrotic enlargement of cone photoreceptor cells and the release of high-mobility group box-1 in retinitis pigmentosa.

Cell death discovery·2016

Treadmill measures of ambulation rates in ovine models of spinal cord injury and neuropathic pain.

Journal of medical engineering & technology·2016

Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium.

Cell death & disease·2015

Macrophage- and RIP3-dependent inflammasome activation exacerbates retinal detachment-induced photoreceptor cell death.

Cell death & disease·2015

Ischemic diabetic retinopathy as a possible prognostic factor for chronic kidney disease progression.

Eye (London, England)·2014

Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors.

Journal of medicinal chemistry·2026

Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections.

Journal of medicinal chemistry·2026

Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8.

Journal of medicinal chemistry·2026

Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight.

Journal of medicinal chemistry·2026

Recent Advances in Antiviral Medicinal Chemistry against Flaviviruses Driven by Multistrategic Approaches.

Journal of medicinal chemistry·2026

A Combined Chemoinformatics- and Machine Learning-Based Approach Identifies Chlormidazole as a Drug Repurposing Candidate against Aggressive Prostate Cancer.

Journal of medicinal chemistry·2026

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals.

Pharmaceutical biology·2026

Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/caspase-3, and TLR4/NF-κB axis activation.

Iranian journal of basic medical sciences·2026

ΔAlaAz cleavable linkers: efficient peptide cleavage in the presence of aromatic thiols and air oxygen.

RSC chemical biology·2026

Vitamin B1-catalyzed green synthesis and antiplasmodial evaluation of 2-amino-7-hydroxy-4-aryl-4H-chromene-3-carbonitrile derivatives: computational insights into putative PfNDH2 targeting.

RSC advances·2026

Click chemistry-based synthesis of fluorescent digitoxin derivatives with anticancer activity and cellular imaging potential.

RSC advances·2026

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Potential naphthoquinone antimalarials. 2-acylhydrazino-1,4-naphthoquinones

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Does intranasal dexmedetomidine provide adequate plasma concentrations for sedation in children: a pharmacokinetic study.

Necrotic enlargement of cone photoreceptor cells and the release of high-mobility group box-1 in retinitis pigmentosa.

Treadmill measures of ambulation rates in ovine models of spinal cord injury and neuropathic pain.

Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium.

Macrophage- and RIP3-dependent inflammasome activation exacerbates retinal detachment-induced photoreceptor cell death.

Ischemic diabetic retinopathy as a possible prognostic factor for chronic kidney disease progression.

Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors.

Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections.

Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8.

Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight.

Recent Advances in Antiviral Medicinal Chemistry against Flaviviruses Driven by Multistrategic Approaches.

A Combined Chemoinformatics- and Machine Learning-Based Approach Identifies Chlormidazole as a Drug Repurposing Candidate against Aggressive Prostate Cancer.

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation.

A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals.

Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/caspase-3, and TLR4/NF-κB axis activation.

ΔAlaAz cleavable linkers: efficient peptide cleavage in the presence of aromatic thiols and air oxygen.

Vitamin B1-catalyzed green synthesis and antiplasmodial evaluation of 2-amino-7-hydroxy-4-aryl-4H-chromene-3-carbonitrile derivatives: computational insights into putative PfNDH2 targeting.

Click chemistry-based synthesis of fluorescent digitoxin derivatives with anticancer activity and cellular imaging potential.

Related Experiment Videos

Potential naphthoquinone antimalarials. 2-acylhydrazino-1,4-naphthoquinones

Related Concept Videos

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