Related Experiment Video
Updated: Jul 12, 2026

Assessing the Secretory Capacity of Pancreatic Acinar Cells
Published on: August 28, 2014
The relationship between flow and electrolyte secretion in the canine pancreas
Abstract:
The response of the pancreatic bicarbonate secretory mechanism to secretin and the relationship between bicarbonate concentration and flow rate in pancreatic juice have been re-examined following reports describing decreasing levels of bicarbonate concentration at high flow rates. Both anaesthetized and chronic fistula dogs were used. The results show that when high doses of secretin elicit high rates of flow of pancreatic juice the bicarbonate concentration rises to a peak which is constant over a wide range of stimulation and flow rates.
Related Concept Videos
Insulin Secretory Vesicles
Cells and Secretions of the Pancreas
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
Pancreatic Juice and Secretion
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
Reabsorption and Secretion in the DCT and Collecting Duct
The distal part of the DCT, along with the...
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are co-secreted in...
Acute Pancreatitis II: Pathophysiology

