The technique and applications of muscle biopsy

The technique of muscle biopsy is described. The precautions in selection, removal and preservation of the biopsied muscle tissue and the need for cooperation between the clinician, surgeon and pathologist in order to obtain the greatest value from the biopsy are stressed. The practical applications of muscle biopsy are presented. Its importance and usefulness in the diagnosis and management of patients with neuromuscular disorders and its potential in research are discussed.