Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Idiopathic hypercalciuria and hyperparathyroidism.

P Adams, T M Chalmers, L F Hill

    British Medical Journal
    |December 5, 1970
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

    Physical review letters·2024
    Same author

    Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

    Physical review letters·2022
    Same author

    Quantifying Brain Iron in Hereditary Hemochromatosis Using R2* and Susceptibility Mapping.

    AJNR. American journal of neuroradiology·2022
    Same author

    SP rTaTME: initial clinical experience with single-port robotic transanal total mesorectal excision (SP rTaTME).

    Techniques in coloproctology·2021
    Same author

    Open-Label Allopregnanolone Treatment of Men with Fragile X-Associated Tremor/Ataxia Syndrome.

    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2017
    Same author

    A computational analysis of flanker interference in depression.

    Psychological medicine·2015
    Same journal

    Muscular pain during therapy with carbenoxolone (Biogastrone).

    British medical journal·2016
    Same journal

    ACUTE INTESTINAL OBSTRUCTION DUE TO INTRA-ABDOMINAL CAUSES.

    British medical journal·2014
    Same journal

    A CASE OF HAEMATIDROSIS.

    British medical journal·2014
    Same journal

    Incidence of ulcer in haematemesis.

    British medical journal·2011
    Same journal

    Pituitary hypothyroidism with impaired renal function.

    British medical journal·2011
    Same journal

    The fenestration operation for otosclerosis.

    British medical journal·2011
    See all related articles

    Provocative tests revealed that 8 of 19 patients with idiopathic hypercalciuria had hypercalcemia, indicating potential parathyroid issues. Four patients with parathyroid adenomas and one with normal glands improved after surgery.

    Area of Science:

    • Nephrology
    • Endocrinology
    • Surgical Pathology

    Background:

    • Idiopathic hypercalciuria is a common cause of kidney stones.
    • The role of parathyroid glands in idiopathic hypercalciuria is not fully understood.
    • Provocative testing can help differentiate causes of hypercalcemia.

    Purpose of the Study:

    • To investigate the prevalence of parathyroid abnormalities in patients with idiopathic hypercalciuria using provocative tests.
    • To assess the effectiveness of parathyroid surgery in managing hypercalciuria associated with hypercalcemia.

    Main Methods:

    • Phosphate deprivation and chlorothiazide administration were used as provocative tests for parathyroid activity.
    • Neck exploration and parathyroidectomy were performed in selected patients.

    Related Experiment Videos

  • Histopathological examination of parathyroid glands was conducted.

    • Main Results:

    • 8 out of 19 patients (42%) with idiopathic hypercalciuria developed hypercalcemia following provocative testing.
    • 4 out of 5 surgically explored patients had parathyroid adenomas.
    • One patient with "normal" glands responded to subtotal parathyroidectomy, while another with hyperplasia did not develop hypercalcemia.

    Conclusions:

    • Parathyroid adenomas are a significant finding in a subset of patients with idiopathic hypercalciuria presenting with hypercalcemia.
    • Surgical intervention, including parathyroidectomy, can be beneficial for select patients.
    • Further research is needed to clarify the precise role of parathyroid function in idiopathic hypercalciuria.