Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

GH secretion in open-angle glaucoma.

A V Greco, B Ricci, L Altomonte

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

    Physical review letters·2025
    Same author

    Use of Levosimendan as bridge therapy to surgical correction of post-infarction ventricular septal defect: a case report.

    European review for medical and pharmacological sciences·2021
    Same author

    Editorial - Lies have short legs.

    European review for medical and pharmacological sciences·2020
    Same author

    Local pesticide use intensity conditions landscape effects on biological pest control.

    Proceedings. Biological sciences·2019
    Same author

    PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma.

    Oncogene·2017
    Same author

    The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.

    Cell death and differentiation·2015
    Same journal

    The risk of retinal vascular events in patients using semaglutide: a scoping review.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
    Same journal

    Interpreting relative afferent pupillary defect in Leber hereditary optic neuropathy using interocular visual acuity difference.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
    Same journal

    1 MONTH VS. 3 MONTHS HEAVY SILICONE OIL TAMPONADE IN COMPLEX RHEGMATOGENOUS RETINAL REDETACHMENT.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
    Same journal

    Visual loss after silicone oil removal - Analysis of a German cohort.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
    Same journal

    Weekend effect on vitrectomy: Insights from a Nationwide Population-Based Study in Korea.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
    Same journal

    The Royal College of Ophthalmologists National Ophthalmology Database Age-related Macular Degeneration (AMD) Audit, Report 2: Baseline characteristics, the care pathway and 12-month visual acuity and safety outcomes for 54,882 eyes starting treatment for neovascular AMD.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2026
    See all related articles

    Open-angle glaucoma may be linked to elevated human growth hormone (HGH) levels. Increased HGH might disrupt ocular pressure regulation by altering aqueous humor flow through the trabecular meshwork.

    Area of Science:

    • Endocrinology
    • Ophthalmology
    • Metabolic Disorders

    Background:

    • Open-angle glaucoma is often observed in acromegaly patients.
    • Acromegaly is characterized by elevated levels of somatotropic hormone (human growth hormone).

    Purpose of the Study:

    • To investigate the potential role of human growth hormone (HGH) in the development of open-angle glaucoma.
    • To explore the relationship between HGH levels and intraocular pressure regulation.

    Main Methods:

    • Measured plasma HGH levels in open-angle glaucoma patients and control subjects.
    • Administered intravenous arginine to stimulate HGH release and observed subsequent HGH levels.
    • Compared HGH levels at 60 and 90 minutes post-arginine administration.

    Related Experiment Videos

    Main Results:

    • Open-angle glaucoma patients exhibited significantly higher plasma HGH levels compared to controls at both 60 and 90 minutes after arginine infusion (p < 0.001).
    • The study supports the hypothesis that elevated HGH may interfere with ocular pressure regulation.

    Conclusions:

    • Increased HGH levels may alter aqueous humor flow by affecting the sclero-corneal trabecular meshwork, potentially contributing to glaucoma.
    • The interaction between HGH and carbohydrate metabolism changes could be a factor in intraocular pressure variations in glaucoma patients.