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[House-dust allergy in bronchial asthma]
Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|December 1, 1979
Summary
House dust mite allergy is a primary cause of atopic asthma. Hyposensitization offers clinical improvement for 50-60% of patients with house dust allergies.
Area of Science:
- Allergy and immunology
- Respiratory medicine
- Clinical research
Context:
- Atopic asthma is a prevalent condition.
- House dust and house dust mites are significant allergens.
- Prevalence rates for house dust allergy and house dust mite allergy are 18.4% and 14.1% respectively.
Purpose:
- To investigate the prevalence of house dust and house dust mite allergies as causes of atopic asthma.
- To determine the role of mite excretions in sensitization.
- To evaluate diagnostic methods and therapeutic interventions.
Summary:
- House dust allergy and house dust mite allergy are the most frequent causes of atopic asthma, affecting 18.4% and 14.1% of the population, respectively.
- Mite excretions are responsible for sensitization in approximately 60% of house dust allergy cases.
- The radio-allergo-sorbent test (RAST) is a reliable method for detecting responsible antibodies, showing about 50% concordance with intracutaneous testing.
- Hyposensitization is an important treatment option, achieving clinical improvement in 50-60% of carefully selected patients.
Impact:
- Highlights the significant role of house dust mites in atopic asthma.
- Validates diagnostic tools for allergy testing.
- Supports hyposensitization as an effective therapeutic strategy for allergic asthma management.