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Glaucoma associated with precipitates on the trabecular meshwork.

M Roth, R J Simmons

    Ophthalmology
    |September 1, 1979
    PubMed
    Summary
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    Precipitates on the trabecular meshwork, a sign of ocular inflammation, often indicate glaucoma unresponsive to standard therapy. Topical steroids effectively treated these precipitates and reduced intraocular pressure.

    Area of Science:

    • Ophthalmology
    • Glaucoma Research
    • Ocular Inflammation

    Background:

    • Trabecular meshwork precipitates can be subtle indicators of underlying ocular disease.
    • Glaucoma associated with these precipitates may present with minimal overt signs of inflammation.
    • Standard antiglaucoma therapies are often ineffective in these specific cases.

    Observation:

    • Fourteen patients with glaucoma and trabecular meshwork precipitates were identified.
    • These patients exhibited minimal or no other clinical signs of ocular inflammation.
    • Conventional antiglaucoma treatments failed to yield positive results for this cohort.

    Findings:

    • Treatment with topical steroids successfully resolved the trabecular meshwork precipitates.
    • Intraocular pressure was significantly lowered following steroid administration.

    Related Experiment Videos

  • The precipitates were directly linked to the inflammatory process causing elevated IOP.

    • Implications:

    • Topical steroids represent an effective treatment for glaucoma linked to trabecular meshwork precipitates.
    • Early and accurate diagnosis via gonioscopy is crucial for appropriate patient management.
    • This finding highlights an alternative therapeutic approach for specific glaucoma subtypes.