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[Allergic reactions in cytostatic therapy].

I Vuković, S Todorović, G Konjević

    Bilten Za Hematologiju I Transfuziju
    |January 1, 1979
    PubMed
    Summary

    Cytostatics used in cancer treatment can cause allergic reactions in children, ranging from mild to severe. Antihistamines effectively resolved these allergic symptoms, aiding in diagnosis and management.

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    Andrology·2015

    Area of Science:

    • Oncology
    • Allergology
    • Pediatrics

    Context:

    • Cytostatics are crucial in treating malignant diseases.
    • Drug-induced hypersensitivity is a known complication of various medications.
    • Allergic reactions can mimic or complicate toxic effects of chemotherapy.

    Purpose:

    • To report on allergic manifestations in children undergoing cytostatic therapy.
    • To highlight the range of allergic reactions observed.
    • To discuss diagnostic challenges and treatment outcomes.

    Summary:

    • This study observed six pediatric patients with malignant diseases who developed allergic reactions during cytostatic treatment.
    • Reactions varied from urticaria to Stevens-Johnson syndrome.
    • Allergic symptoms resolved with antihistamine administration.
    • Differentiating allergic reactions from direct toxic effects of cytostatics posed diagnostic challenges.

    Impact:

    • Recognizing and managing cytostatic-induced allergies is vital for pediatric cancer care.
    • Prompt antihistamine treatment can alleviate symptoms and improve patient outcomes.
    • Awareness of potential allergic reactions aids in differential diagnosis, preventing misattribution to drug toxicity.

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