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Erosive lichen planus and cirrhotic hepatitis
Italian General Review of Dermatology
|May 1, 1978
Summary
Erosive lichen planus patients often develop liver complications, with five of seven showing cirrhosis. Two patients were diagnosed with active chronic hepatitis through laparoscopy and liver biopsy.
Area of Science:
- Hepatology
- Dermatology
- Gastroenterology
Background:
- Erosive lichen planus (ELP) is a chronic inflammatory condition.
- The association between ELP and liver disease requires further investigation.
Purpose of the Study:
- To investigate the prevalence of liver complications in patients diagnosed with erosive lichen planus.
Main Methods:
- Retrospective analysis of seven patients with erosive lichen planus.
- Diagnostic procedures included laparoscopy and liver biopsy for two patients.
Main Results:
- Five out of seven (71.4%) patients with ELP presented with cirrhotic liver complications.
- Two patients were confirmed to have active chronic hepatitis via liver biopsy and laparoscopy.
Conclusions:
- A significant proportion of patients with erosive lichen planus exhibit underlying liver pathology, particularly cirrhosis.
- Further research is warranted to elucidate the pathogenic mechanisms linking ELP and chronic liver disease.