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Abnormal intestinal flora.

S Tabaqchali

    Annali Dell'Istituto Superiore Di Sanita
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    The small intestine typically has few Gram-positive microbes. Bacterial overgrowth in the small intestine can lead to metabolic issues, prompting a review of these conditions and their consequences.

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    Area of Science:

    • Microbiology
    • Gastroenterology
    • Human Physiology

    Background:

    • The small intestine normally hosts a sparse microflora, primarily Gram-positive microorganisms from the oro-pharynx.
    • Bacterial concentrations increase from the jejunum (10^3-10^4 organisms/ml) to the ileum (10^5-10^6 organisms/ml), including fecal-type bacteria.
    • Small intestinal integrity is crucial for maintaining this microbial balance.

    Purpose of the Study:

    • To identify conditions associated with bacterial overgrowth in the small intestine.
    • To characterize the microflora colonizing the small intestine in these conditions.
    • To discuss the metabolic consequences of small intestinal bacterial proliferation.

    Main Methods:

    • Literature review to identify conditions causing bacterial proliferation.

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  • Description of microflora composition based on existing studies.
  • Discussion of metabolic consequences derived from scientific literature.

    • Main Results:

    • Identified specific conditions leading to abnormal bacterial proliferation in the small intestine.
    • Characterized the types of microorganisms (e.g., Enterobacteria, Bifidobacteria, Bacteroides) involved in small intestinal dysbiosis.
    • Outlined various metabolic abnormalities associated with bacterial overgrowth.

    Conclusions:

    • Bacterial proliferation in the small intestine, when it occurs, disrupts normal physiology.
    • Understanding the conditions, microflora, and metabolic effects is key to addressing small intestinal dysbiosis.
    • Further research into the metabolic consequences can inform clinical management.