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Related Concept Videos

Intracellular Hormone Receptors01:08

Intracellular Hormone Receptors

Lipid-soluble hormones diffuse across the plasma and nuclear membrane of target cells to bind to their specific intracellular receptors. These receptors act as transcription factors that regulate gene expression and protein synthesis in the target cell
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Related Experiment Video

Updated: Jul 10, 2026

Imaging of Estrogen Receptor-α in Rat Pial Arterioles using a Digital Immunofluorescent Microscope
07:42

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Published on: November 29, 2011

[Estrogen receptors in rabbit thymus].

N Panza, P Mondola, C Falconi

    Bollettino Della Societa Italiana Di Biologia Sperimentale
    |December 30, 1979
    PubMed
    Summary

    The study investigated estrogen receptors in female rabbit thymus tissue. Results indicate low levels of estrogen-binding proteins, suggesting they are not entirely absent.

    Area of Science:

    • Endocrinology
    • Immunology
    • Cell Biology

    Context:

    • The thymus gland plays a crucial role in the immune system.
    • Estrogen receptors (ER) are key mediators of estrogen's effects in various tissues.
    • Understanding ER presence in the thymus is vital for comprehending potential estrogenic modulation of thymic function.

    Purpose:

    • To determine the presence and levels of cytoplasmic and nuclear estrogen receptors in the female rabbit thymus.
    • To assess the potential for estrogenic action within the thymus gland.

    Summary:

    • Cytoplasmic estrogen receptors were measured in female rabbit thymus using sucrose gradient, protamine sulphate, and dextran-coated charcoal assays.
    • Nuclear ER presence was investigated in thymic pellet fractions via sucrose gradient assay.

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  • The findings exclude high concentrations of estrogen-binding proteins but do not rule out their complete absence in the female rabbit thymus.

    • Impact:

    • Provides foundational data on estrogen receptor expression in the rabbit thymus.
    • Informs future research on the role of estrogens in thymic immunity and development.
    • Contributes to the broader understanding of endocrine-immune interactions.