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Pardoxical cytotoxic effect of antisera used in diagnostic virology. Brief report
Zentralblatt Fur Bakteriologie, Parasitenkunde, Infektionskrankheiten Und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie Und Parasitologie
|February 1, 1977
Abstract:
Rabbit antisera prepared against adenovirus-infected or uninfected HEK cells showed a high degree of cytotoxicity towards HeLa and other human cell cultures, while antisera prepared against infected HeLa cells did not. The toxic activity was independent of complement; it could be removed by adsorption to HEK monolayers.