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Congenital pericardial diaphragmitic hernia and multiple cardiac defects in a litter of collies
Journal of the American Veterinary Medical Association
|March 1, 1977
Insights
Congenital cardiac and diaphragmatic anomalies were observed in Collie littermates. While defects were present, evidence suggests they were congenital, not hereditary, in this canine study.
Area of Science:
- Veterinary Cardiology
- Congenital Malformations
- Canine Genetics
Background:
- This study investigates a litter of Collie dogs exhibiting multiple congenital anomalies.
- Understanding the etiology of congenital defects in purebred dogs is crucial for breeding programs and veterinary diagnostics.
Observation:
- Four Collie littermates presented with significant cardiac and diaphragmatic abnormalities.
- Specific cardiac defects included ventricular septal defect, pulmonic stenosis, atrial septal defect, and mitral regurgitation.
- Pericardial diaphragmatic hernia was also noted in three of the affected littermates.
Findings:
- A high prevalence of multiple congenital anomalies was observed within the Collie litter.
- The observed defects were classified as congenital, indicating they were present at birth.
- Available evidence did not support a hereditary basis for these specific anomalies in this cohort.
Implications:
- These findings highlight the potential for complex congenital malformations in certain canine breeds.
- Further research into the genetic and environmental factors contributing to such defects is warranted.
- This case study provides valuable data for veterinary diagnosticians and canine breeders.
Abstract:
Four Collie littermates had multiple cardiac and diaphragmatic anomalies. Ventricular septal defect was found in 3, pulmonic stenosis in 2, atrial septal defect in 1, mitral regurgitaion in 1, and pericardial diaphragmatic hernia in 3. Five additional littermates died within 72 hours of birth but were not necropsied. On the basis of available evidence, it was believed that the defects were congenital but not hereditary.