[Reaginic immunological responses in rats and mice]

Reaginic immunological responses present characteristics of induction which differentiate them from classical antibodies responses from other classes: among them we studied, on the one hand, the genetic control. In the case of OVO-DNP reaginic antibodies in the rat, the controls exercised by the Ag-B haplotypes or the synthesis loci of the immunoglobulin heavy chains does not seem to be sufficient to explain the experimental results. Another control exist probably. It could be linked to the global IgE serum level control; on the other hand, the IgE plasma cells. In rats infested with Nippostrongylus brasiliensis, they make their appearance in large number in the mesenteric lymph node but not in the lamina propria of the intestinal mucosa.